Wednesday, May 30, 2012

Presentations start-ups to the public



I want to draw attention to a very. interesting trend. interesting trend in presentations startups.

We 're not talking about the investor presentations, we will talk about different projects, competitions.

Over the past three years I was able to visit the 13 contests and have feedback. fidbeki. by another 12. And this is an interesting trend in the development. what trend. I noticed.
Three years ago in 2005 in most cases dominated. dominated. Format 20 ( minutes per report) 10 ( to questions from the audience ), or May 20. Even then it was evident that a series of several presentations ( 4-8) is very difficult given the judges, the more eminent judges and those who did not like this project, frankly do not listen and were dissatisfied with the murder of the time. And I began to visit the idea that it would be nice to turn this thing in 15 15. 15 should be enough crumple, and 15 minutes listening to the question -answer still more interesting.

It seems that these thoughts are not visited me one and after some time (years) became popular standard for May 15, which is closer to the subject. Most of the presentations of the projects have to be more interesting. Immediately began to play the human factor to 15 minutes to light the investor should try to. In these presentations it became clear who heads the team, as he charismatic. Contests began to hold a meeting with reporters before the show (to weed out those who were not a great orator ). Many contests have been actively working with proketami helping them become more attractive to potential students presentations. to do coaching. projects. Then I began to visit the idea that in this situation, the wide field of action for fraud, but if the selection committee is working well, a good project with a strong leader, has clear advantages.
Tekranch. Techcrunch last year introduced a rule September 1. The contest was held with a bang. Last but not least the fact that he has collected the best designs, but also by the fact that he put very strict rules and inflated rates.
This year in Europe began to emerge format 7 minutes. What more complicated task for the project. But the struggle has made even more acute. At the next event ( 17th April), let's see how it looks live.
One happy that all the judges usually see. Executive Summary. Short Description of Project Executive prior to performance.
In this case, starts an emotional factor. We will not display with your fingers, but one of the competitions speaker came with a guitar, blew the audience and received high marks. Meeting with the judges after given a single opinion - ...

The questions arise:.
- How long? . elevetor speech. *) ( 30-40 seconds )? .
- What are ways you can use non-trivial nature of the project reports to the audience?.
- A can do a good startup does not require a great presentation, if the idea is good its all caught on the fly ( as well as I had not thought of this before? )?.

more. One interesting trend is. one interesting develop - it is tightening the criteria for admission to the presentation. I have seen when they tried to avoid the draft did not. rating of. better definition of the project by setting a descending scale of assessments to posleduschego summation, and. absolute consensus. unanimous consent of all judges - up from 40 projects and 9 judges in the finals two projects. I had to replay.

So a special thank you to all who dropped karma.
PS. There is an opinion that the tenders submitted. losers. Losers. Good design and so will the money. I disagree with him, but something in it, will agree.

PPS. Corrections made ​​at the request of readers.

*) Elevator pitch. Short presentation of the project, which is used if the student was caught on the road and he has no more than 30-40 seconds and he can not focus more attention on the subject of conversation, distracted by external stimuli ( passers-by, mobile phone, etc. Dr.. ). Implies brevity and emotional. Usually used in a confined space (for example, in the elevator ) when listeners have nowhere to go, or on the way from the office ( working space ) to the parking lot where the car is parked. The author does not know Russian analogue of the expression ideomaticheskogo.

** ) Presentation. - A demonstration project to the public, in this case, students are key investors, from the English presentation.

***) Investors. - Natural or legal persons who are willing to make to the statutory fund start-up some of the money in exchange for part ownership in the startup, from the British investor.

****) Startup.

So politically correct enough?.

PSSS. In kindergarten the tragedy, the children began to swear. Investigated, it turns out during the repair of garden, one soldier to another shed on the head of tin. Polkan asked the victim:.
- So what did you say?.
- I said: ' Private Ivanov, you do not see that the molten metal dripping on your head to your comrade? ...

Friday, May 25, 2012

14 months for the two passwords


The Court summed up the city of Cheboksary in the criminal case over the 21 -year-old student, who in early 2007 broke the mailbox of one of the clients Yandex. Mail and tried to use the data to Yandex. purse.





The court, after reviewing all the evidence, the offender was sentenced under Article 272 h. 1 of the Criminal Code of the Russian Federation ( illegal access to computer information protected by law ) to one year and two months' imprisonment.





According to the deputy chief of the press center of the Russian Interior Ministry Klimovsk Paul, this is not a single fact in the successful operation of the detention of such scams. Today, the Russian Interior Ministry branch departments establish contacts with Russian Internet companies, and they, in turn, assist in the successful solving crimes of this kind.



Old age is canceled!




Старость можно отменить?

Старость можно отменить?

Maxim Skulachev / / Kommersant.

We were able to talk to his son, Maxim Skulachev, member of the project, to. b. n. , Director of the Institute of Moscow State University Mitoinzhenerii «Mitotech».








- What is your project?.

- In the late '60s and early '70s was made one of the greatest discoveries in the biology of the twentieth century, it was determined where in the body takes the energy. Before that, people knew that the intracellular organelles - the mitochondria - consume oxygen and produce energy, but how they do it, no one understood. The brilliant biochemist Peter Mitchell from the UK suggested that in the process of storing energy - combustion in oxygen of nutrients - in the membrane of the mitochondria formed an electric potential, which is the primary energy ... He predicted the existence of this power, and proved it was the Moscow State University, in the laboratory of Vladimir Petrovich Skulachev, using substances that can penetrate into the mitochondria and there is accumulating. These substances were identified Skulachev ions, since he was the first ... Since Skulachev ions accumulate only in the mitochondria, then if they are ... For example, antioxidants - because mitochondria provide us with not only energy, but also by free radicals. Many people think that free radicals - that's what came out of the air into the body or out of a bad environment. But the major part of them we manufacture ourselves. Accordingly, there is good reason to think that if you remove the excess free radicals in mitochondria, life will get better. By the way, with age, our mitochondria produce more and more of these radicals. And from this came the idea of ​​the unexpected application of these antioxidants delivered to the mitochondria, what might they impact on the process of aging, because they can reduce the level of free radicals. And this is our project was born, so it is clear that such substances can make drugs that have very high biological activity, and possibly even a cure for the extension of youth.



- How exactly will this work ...
- It's true, and so. The only way to convey to the human synthetic substance - making him the medicine. And it can only be on the disease - cardiac arrhythmia, macular degeneration, stroke, etc. n.



Therefore, the main things which we are now working - this is medicine for diseases. And if we will have good luck, and it turns out that a certain set of diseases we can cure, then we expect to reach physicians and say, ... And in general - look at their photos! . So let's have already recognize that a substance that preserves youth ... Of course, this is an optimistic scenario. The overall plan is that over the next 10-12 years will be a cure for specific diseases, and then, if all goes well, and if you can track the history of the disease those people who were treated with this medicine, then perhaps we can prove that it affects .



- That is a perfect remedy? .
- A number of diseases, which are aimed at these medicines today are considered incurable, they are simply no drugs. For example, retinal degeneration. Here, we aspire to create a ... And in some cases - stroke, heart arrhythmia - in fact, there is a huge number of drugs. But also a lot of patients, they are insensitive. And perhaps there is need to rely on a combination of drugs - our own and other. Because it would be foolish to assume that an antioxidant can cure everything.



- What caused the aging?.

- There are two views on aging - pessimistic and optimistic. First - this is a classic idea that this is the inevitable accumulation of errors, all mutations and damage. The more you live, the more they accumulate, and eventually die. And we are optimists believe that everything is arranged differently, there is a special genetic program, which we deliberately driving into the pit and does not allow us to live longer than a certain age. And it not only limits the life span, but also makes us gradually grow old, decrepit. The optimism of this approach is that, if aging - the accumulation of random errors, then there is nothing that can not be done. And you need to protect against these errors, all the organs, it is virtually impossible. And if it's genetic program, it is very easy to break. And this can be done in one substance, one small place settings of this program, and do not necessarily protect the entire body from everything.



- T. e. the body will give a team does not get old?.

- He will not give a command to the aging.



- And why is everyone will die?.

- There are many causes of death other than old age. There is a disease - heart attacks are the same - that there are no age, but from some unfortunate combination of circumstances. At the head may drop a brick, have mental health problems, a huge number of road accidents. And we really do not know how people will live, if you disable a program of aging.



- That is, people will not get sick, will not grow old and die, unless it happens to the accident? .

- Throughout its history, people are gradually cut off the main causes of death - hunger, cold, predators, infectious diseases. And all the time, got out some new. What is most interesting - the maximum duration of his life has not changed. Since ancient times as they lived 80-90 years old, and live. Another thing that used to live to 80 years was a great event, and now it is a mass phenomenon. That is to say it has increased the average life expectancy rather than maximum. Centuries- old men were in the seventeenth century. A 150 -year-olds as there was then, so there is now. In the early twentieth century the invention of anesthesia and antibiotics, prolonged the life of a person (on average) at times. If at the beginning of the twentieth century, someone fell ill with pneumonia, it has already been sentenced. A penicillin canceled this program and gave the man a chance to live longer. And has anything changed in society? . But this man and then dies of a cause of the next - for example, from cardiovascular disease. Therefore, I am sure that if we cancel a program of aging, then all will live in good condition up to 80-90 years - but not until 200 years. And most likely, again, there will some new cause of death. I do not believe that anti- aging program, you can essentially extend the maximum age of the person.



- Now your project is moved to a new level - what is it?.

- We are now closer than ever to the most interesting things in the biologist - to test in humans. We have already begun their preparations for our eye. But the real breakthrough would be if the experiment on humans to confirm that we have seen in animals.



- To whom you are testing a drug?.

- The volunteers. Vladimir Petrovich ( Skulachev 's father - a comment. Red. ) Of course, extremist, and tried it on himself, but he - the only one who has the right to do as the inventor. For the rest of it is strictly prohibited. By the way, it would be nice to voice it in your article, since we are tortured by sick people who call asking for his medication, but do not strictly.



- Explain, please phrase your father's ...
- Indeed, the aging species evolve faster. A very simple example - the ... Suppose we have two hares, one of which took place some sort of mutation, and now he's smarter than the other. While they are both young, they are great escape from the fox, and wise there is no advantage. But that's starting to get old rabbits, slower running. And then one that is smarter - which saw a fox earlier and better than your way - run away, and another, the usual, eat. And those who escaped, smart spawn leverets and give their ...



Then we have a generation ... Otherwise, it would take thousands of years, and it happens in one season. It follows from this hypothesis that the species that came up with something that allowed him to solve their problems once and for which the pressure of the environment is very weak, does not require aging. After all, he does not evolve, does not lead the fight for survival. For example, not very clear why accelerate the evolution of an octopus - they are the kings of the sea, the most intelligent, powerful, fast. Accordingly, they do not age. After breeding the female simply stops eating and dies of starvation. They have their own programs, but there is this humiliating period of decay. And the de facto person has already passed in this state. We do not use evolution, and aging we do not need.



- The religious fanatics did not accuse you that you interfere in the natural process?.

- We get involved in it any more than the inventor of antibiotics. On the contrary, it is pleasing to God - life-saving.



- But apart from the negative aspects of aging, there are positive. For example, there is a natural slow rhythm of life, people want to pay less attention to work, messing around with his grandchildren.
- I 'm not sure that 70 year share your point of view. And they want to go to work, especially if the work was the meaning of their lives. I know many who are retiring killed. Besides the fact that we are doing is absolutely voluntary. Our task in any case does not make people live longer, and give people a choice. Now it is not.



And I do not see any negative aspects. There will be fewer old men sitting in front of TV. Of course, this series will hit the market and advertising, but I hope to raise the market of products for babies. This, of course, science fiction, but on the other hand, this should seek to. Now everyone thinks - ... But why? .



Discovery Skulachev says Konstantin Severinov, Dr.. b. n.



Rutgers University Professor of the United States, heads of laboratories of the Institutes of Molecular Genetics and Gene Biology, RAS:.




... Indeed, an important conceptual problem of aging is to establish its causes: whether it is associated with a variety of injuries accumulated during life, or due to some kind of special program. In general, adherents of the first point of view today is clearly greater, and that would be a natural carrier of aging program at present is not clear. In my view, recognition of ... In fact, many scientists are developing therapies to replace damaged cells and tissues. These approaches can in principle be in the future is really significantly delay the aging. In fact, developed in the laboratory Skulachev matter, this is also highly effective antioxidants, which just eliminate the cellular damage that accumulates during metabolism ...








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Tuesday, May 22, 2012

Sunday, May 13, 2012

DEPECHE MODE - Devotional Ultimate (LIVE 93 - 94)













Description:.
Tracklist:.
Intro.
Higher Love.
Policy Of Truth.
World In My Eyes.
Walking In My Shoes.
Behind The Wheel.
Halo.
Stripped.
Condemnation.
A QUESTION OF LUST.
ONE CARRES.
Mercy In You.
I Feel You.
Never Let Me Down Again.
Rush.
In Your Room.
Personal Jesus.
Enjoy The Silence.
Fly On The Windscreen.
Everything Counts.




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